Thalidomide-NH-C4-NH-Boc
This synthesized conjugate features a thalidomide-based cereblon ligand connected via a C4-amine linker with a Boc-protected terminus, designed for PROTAC development. It serves as a key intermediate for constructing bifunctional degraders used in targeted protein degradation research, applicable in both cellular and biochemical assays.
Product Specifications
CAS Number
2093388-52-2
Product Name Alternative
Cereblon, E3 Ligase LigandLinker Conjugate, E3 Ligase Ligand-Linker Conjugates, E3 Ligase Ligand-Linker Conjugate, E3LigaseLigandLinkerConjugate, Ligand for E3 Ligase, LigandforE3Ligase, inhibit, Inhibitor, Thalidomide NH C4 NH Boc, Thalidomide, ThalidomideNHC4NHBoc, Thalidomide-NH-C-4-NH-Boc, Thalidomide-NH-C4-NH-Boc, PROTAC
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
98.72% (May vary between batches)
Solubility
DMSO:50 mg/mL (112.49 mM) ;10% DMSO+90% Saline:2.5 mg/mL (5.62 mM)
Smiles
O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2NCCCCNC (OC (C) (C) C) =O
Molecular Formula
C22H28N4O6
Molecular Weight
444.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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