Thalidomide-O-amido-PEG-C2-NH2 hydrochloride
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a cereblon-binding ligand-linker conjugate designed for constructing PROTAC degraders. This compound enables the targeted degradation of proteins of interest and is a key reagent for chemical biology research in both cellular and preclinical models.
Product Specifications
CAS Number
2204226-02-6
Product Name Alternative
E3LigaseLigandLinkerConjugate, Inhibitor, inhibit, E3 Ligase LigandLinker Conjugate, E3 Ligase Ligand-Linker Conjugate, E3 Ligase Ligand-Linker Conjugates, Cereblon, ThalidomideOamidoPEGC2NH2 hydrochloride, Thalidomide-O-amido-PEG-C-2-NH2 hydrochloride, Thalidomide-O-amido-PEG-C2-NH2 Hydrochloride, Thalidomide O amido PEG C2 NH2 hydrochloride
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
95.00% (May vary between batches)
Solubility
H2O:100 mg/mL (219.85 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.79 mM) ; DMSO:125 mg/mL (274.81 mM)
Smiles
Cl.NCCOCCNC (=O) COc1cccc2C (=O) N (C3CCC (=O) NC3=O) C (=O) c12
Molecular Formula
C19H23ClN4O7
Molecular Weight
454.862
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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