Inauhzin
Inauhzin is a novel SIRT1 inhibitor that reactivates p53, inducing p53-dependent apoptosis in human cancer cells like A549 (IC50=3 μM) without significant genotoxicity. It serves as a valuable chemical probe for researching p53 biology, cancer mechanisms, and apoptosis in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
309271-94-1
Product Name Alternative
Sirtuin, SIRT1, Inauhzin, INZ, Inhibitor, inhibit, MDM-2/p53
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Purity
97.69% (May vary between batches)
Solubility
DMSO:45 mg/mL (95.83 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.26 mM)
Smiles
CCC (Sc1nnc2c (n1) [nH]c1ccccc21) C (=O) N1c2ccccc2Sc2ccccc12
Molecular Formula
C25H19N5OS2
Molecular Weight
469.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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