UNC0224
UNC0224 is a potent and selective small molecule inhibitor of the histone methyltransferases G9a (Ki = 2.6 nM) and GLP. It is a valuable chemical probe for epigenetic research, enabling the study of histone methylation roles in cancer biology, neurodevelopment, and other cellular processes in both in vitro and in vivo models.
Product Specifications
CAS Number
1197196-48-7
Product Name Alternative
Chromatin, Inhibitor, Histone Methyltransferase, HistoneMethyltransferase, GLP, H3K9, G9a, p53, lysine, inhibit, K373, stabilized, SAR, PKMT, quinazoline, UNC0224, UNC-0224, UNC 0224
Field of Research
Epigenetics & Chromatin, Stem Cell & Developmental Biology
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (50 mg/ml)
Smiles
COc1cc2c (NC3CCN (C) CC3) nc (nc2cc1OCCCN (C) C) N1CCCN (C) CC1
Molecular Formula
C26H43N7O2
Molecular Weight
485.7
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
7-[3- (Dimethylamino) propoxy]-2- (hexahydro-4-methyl-1H-1,4-diazepin-1-yl) -6-methoxy-N- (1-methyl-4-piperidinyl) -4-quinazolinamine
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