UNC0321
UNC0321 is a potent and selective small-molecule inhibitor of the histone methyltransferases G9a (Ki = 63 pM) and GLP. It is a valuable chemical probe for epigenetic research, enabling the study of histone methylation's role in gene expression, cellular differentiation, and disease models in both in vitro and in vivo settings.
Product Specifications
CAS Number
1238673-32-9
Product Name Alternative
Inhibit, K373, p53, G9a, GLP, H3K9, H3K9me2, Inhibitor, HistoneMethyltransferase, Histone Methyltransferase, PKMT, SAR, quinazoline, UNC 0321, UNC0321, UNC-0321
Field of Research
Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery
Purity
99.25% (May vary between batches)
Solubility
DMSO:3.33 mg/mL (6.46 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.94 mM)
Smiles
COc1cc2c (NC3CCN (C) CC3) nc (nc2cc1OCCOCCN (C) C) N1CCCN (C) CC1
Molecular Formula
C27H45N7O3
Molecular Weight
515.69
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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