Val-cit-PAB-OH
Val-cit-PAB-OH is a cleavable linker used in the development of antibody-drug conjugates (ADCs) . This protease-sensitive spacer enables targeted drug release and is widely utilized in both in vitro and in vivo cancer research to enhance therapeutic efficacy and specificity.
Product Specifications
CAS Number
159857-79-1
Product Name Alternative
Cleavable, Antibody-drug conjugates linkers, ADCLinker, ADC Linkers, ADC Linker, Inhibitor, inhibit, Val cit PAB OH, ValcitPABOH, Val-cit-PAB-OH
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
99.11% (May vary between batches)
Solubility
DMSO:100 mg/mL (263.54 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.54 mM)
Smiles
CC (C) [C@H] (N) C (=O) N[C@@H] (CCCNC (N) =O) C (=O) Nc1ccc (CO) cc1
Molecular Formula
C18H29N5O4
Molecular Weight
379.45
Storage Conditions
-20°C
Notes
For research use only.
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