Vidupiprant
Vidupiprant (AMG 853) is a potent dual CRTH2 and DP receptor antagonist, exhibiting IC50 values of 8 nM and 35 nM, respectively, in human plasma. It serves as a valuable research tool for investigating asthma pathophysiology and has been utilized in both in vitro binding assays and in vivo models of allergic inflammation.
Product Specifications
CAS Number
1169483-24-2
Product Name Alternative
Inhibit, Inhibitor, orally, CRTH2, AMG 009, AMG 853, AMG853, AMG-853, acid, cAMP, asthma, PGD2, phenylacetic, Prostaglandin Receptor, ProstaglandinReceptor, Vidupiprant
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
97.16% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (5.41 mM) ; DMSO:95 mg/mL (155.87 mM)
Smiles
CC (C) (C) NC (=O) c1ccc (Oc2cc (F) c (CC (O) =O) cc2Cl) c (NS (=O) (=O) c2ccc (cc2Cl) C2CC2) c1
Molecular Formula
C28H27Cl2FN2O6S
Molecular Weight
609.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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