Y-27632 dihydrochloride
Y-27632 dihydrochloride is a potent, cell-permeable inhibitor targeting ROCK-I and ROCK-II kinases. It is widely used in vitro to study cytoskeletal dynamics and cell adhesion, and in vivo to investigate pathways in neuroprotection, cardiovascular function, and stem cell survival.
Product Specifications
CAS Number
129830-38-2
Product Name Alternative
Epithelial-mesenchymal, hIPSCs, Inhibitor, inhibit, lineage, mesendodermal, orally, pluripotent, modulation, Apoptosis, ATP-competitive, active, cells, Y27632, Y-27632, Y-27632 2HCl, Y27632 Dihydrochloride, Y27632 dihydrochloride, Y-27632 Dihydrochloride, Y 27632, Y 27632 Dihydrochloride, Y 27632 dihydrochloride, Rho-kinase, ROCK1 (p160ROCK), ROCK2, ROCK, ROK, Rho-associated protein kinase, Rho-associated kinase, transition-like, stem
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.96% (May vary between batches)
Solubility
H2O:32.03 mg/mL (100.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (15.61 mM) ; DMSO:255 mg/mL (796.23 mM)
Smiles
Cl.Cl.C[C@@H] (N) [C@H]1CC[C@@H] (CC1) C (=O) Nc1ccncc1
Molecular Formula
C14H21N3O·2HCl
Molecular Weight
320.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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