WR-99210
WR99210 hydrochloride is a subnanomolar inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), effective against wild-type and multidrug-resistant mutant strains. This compound is a critical research tool for studying antimalarial drug resistance mechanisms and for conducting both in vitro enzyme assays and in vivo efficacy studies in malaria models.
Product Specifications
CAS Number
30711-93-4
Product Name Alternative
PfDHFR, WR 99210, WR99210, WR99210 hydrochloride (47326-86-3 free base), 6,6-Dimethyl-1-[3- (2,4,5-trichlorophenoxy) propoxy]-1,6-dihydro-1,3,5-triazine-2,4-diamine
Field of Research
Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology
Purity
97.77% (May vary between batches)
Solubility
DMSO:55 mg/mL (127.57 mM)
Smiles
NC1=NC (N) =NC (C) (C) N1OCCCOC2=CC (Cl) =C (Cl) C=C2Cl.[H]Cl
Molecular Formula
C14H19Cl4N5O2
Molecular Weight
431.14
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TE21478FHB 1 Piece
Classic 13 boxes 50mm 741x140x140 w/locking rod fixed handle
Sign In for Pricing
View Details 
MBS4380261-01 0.02 mg (With BSA & Azide at 0.2mg/mL)
Topoisomerase II alpha (Proliferation & Drug-Resistance Marker)
Sign In for Pricing
View Details MBS4380261-02 0.1 mg (With BSA & Azide at 0.2mg/mL)
Topoisomerase II alpha (Proliferation & Drug-Resistance Marker)
Sign In for Pricing
View Details MBS4380261-03 0.1 mg (Without BSA & Azide at 1mg/mL)
Topoisomerase II alpha (Proliferation & Drug-Resistance Marker)
Sign In for Pricing
View Details MBS4380261-04 5x 0.1 mg (With BSA & Azide at 0.2mg/mL)
Topoisomerase II alpha (Proliferation & Drug-Resistance Marker)
Sign In for Pricing
View Details MBS4380261-05 5x 0.1 mg (Without BSA & Azide at 1mg/mL)
Topoisomerase II alpha (Proliferation & Drug-Resistance Marker)
Sign In for Pricing
View Details