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WR-99210

WR99210 hydrochloride is a subnanomolar inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), effective against wild-type and multidrug-resistant mutant strains. This compound is a critical research tool for studying antimalarial drug resistance mechanisms and for conducting both in vitro enzyme assays and in vivo efficacy studies in malaria models.

Product Specifications

CAS Number

30711-93-4

Product Name Alternative

PfDHFR, WR 99210, WR99210, WR99210 hydrochloride (47326-86-3 free base), 6,6-Dimethyl-1-[3- (2,4,5-trichlorophenoxy) propoxy]-1,6-dihydro-1,3,5-triazine-2,4-diamine

Field of Research

Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology

Purity

97.77% (May vary between batches)

Solubility

DMSO:55 mg/mL (127.57 mM)

Smiles

NC1=NC (N) =NC (C) (C) N1OCCCOC2=CC (Cl) =C (Cl) C=C2Cl.[H]Cl

Molecular Formula

C14H19Cl4N5O2

Molecular Weight

431.14

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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