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YKL-05-099

YKL-05-099 is a potent and selective salt-inducible kinase (SIK) inhibitor, with IC50 values of 10 nM, 40 nM, and 30 nM for SIK1, SIK2, and SIK3, respectively. This tool compound is widely used in biochemical and cellular research to investigate SIK signaling pathways in inflammation, metabolism, and bone homeostasis.

Product Specifications

CAS Number

1936529-65-5

Product Name Alternative

Inhibitor, inhibit, SIK3, SIK2, SIK1, YKL05099, YKL-05-099, YKL 05 099, Salt-inducible Kinase (SIK)

Field of Research

Signal Transduction

Purity

99.22% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.33 mM) ; DMSO:45 mg/mL (74.99 mM)

Smiles

COc1ccc (nc1) N1C (=O) N (Cc2cnc (Nc3ccc (cc3OC) C3CCN (C) CC3) nc12) c1c (C) cccc1Cl

Molecular Formula

C32H34ClN7O3

Molecular Weight

600.11

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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