YKL-05-099
YKL-05-099 is a potent and selective salt-inducible kinase (SIK) inhibitor, with IC50 values of 10 nM, 40 nM, and 30 nM for SIK1, SIK2, and SIK3, respectively. This tool compound is widely used in biochemical and cellular research to investigate SIK signaling pathways in inflammation, metabolism, and bone homeostasis.
Product Specifications
CAS Number
1936529-65-5
Product Name Alternative
Inhibitor, inhibit, SIK3, SIK2, SIK1, YKL05099, YKL-05-099, YKL 05 099, Salt-inducible Kinase (SIK)
Field of Research
Signal Transduction
Purity
99.22% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.33 mM) ; DMSO:45 mg/mL (74.99 mM)
Smiles
COc1ccc (nc1) N1C (=O) N (Cc2cnc (Nc3ccc (cc3OC) C3CCN (C) CC3) nc12) c1c (C) cccc1Cl
Molecular Formula
C32H34ClN7O3
Molecular Weight
600.11
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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