Guggulsterone (Z-)
(Z) -Guggulsterone induces apoptosis in human prostate cancer cells and exhibits anti-angiogenic properties by inhibiting the VEGF-VEGFR2-Akt signaling pathway. This small molecule is utilized in oncology research for studying cell proliferation and tumor angiogenesis in both in vitro and in vivo models.
Product Specifications
CAS Number
39025-23-5
Product Name Alternative
(Z) Guggulsterone, (Z) Guggulsterone, (Z) -Guggulsterone, Akt, Apoptosis, Inhibitor, Guggulsterone, inhibit, PKB, Protein kinase B, Vascular endothelial growth factor receptor, VEGF-R2, VEGFR
Field of Research
Immunology & Inflammation, Neuroscience, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
FXR antagonist
Form
Powder
Solubility
Soluble in DMSO (up to 6 mg/ml with warming) or in Ethanol (up to 3 mg/ml with warming)
Smiles
C\C=C1/C (=O) C[C@H]2[C@@H]3CCC4=CC (=O) CC[C@]4 (C) [C@H]3CC[C@]12C
Molecular Formula
C21H28O2
Molecular Weight
312.45
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(Z) -Pregna-4,17 (20) -diene-3,16-dione
Available Sizes
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