AL 082D06
AL 082D06 (D-06) is a potent and selective nonsteroidal glucocorticoid receptor (GR) antagonist with a Ki of 210 nM. It demonstrates excellent selectivity, showing negligible affinity for AR, ER, MR, and PR (Ki > 10 μM) . This compound is a valuable research tool for investigating GR-mediated pathways in both cellular and animal models of inflammation, metabolism, and stress response.
Product Specifications
CAS Number
256925-03-8
Product Name Alternative
Inhibitor, GlucocorticoidReceptor, Glucocorticoid Receptor, inhibit, AL 082D06, AL 082D-06, AL082D06, D 06, D06, D-06
Field of Research
Metabolism Research
Purity
≥95% (May vary between batches)
Solubility
DMSO:7.5 mg/mL (18.3 mM)
Smiles
CN (C) c1ccc (cc1) C (c1ccc (cc1) N (C) C) c1cc (ccc1Cl) [N+] ([O-]) =O
Molecular Formula
C23H24ClN3O2
Molecular Weight
409.91
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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