LY2090314

LY2090314 is a potent and selective GSK-3α/β inhibitor (IC50: 1.5 nM/0.9 nM) investigated for its potential to enhance platinum chemotherapy. It has been studied in preclinical models and clinical trials for applications in leukemia, advanced solid tumors, and pancreatic cancer research.

Product Specifications

CAS Number

603288-22-8

Product Name Alternative

3- (9-Fluoro-2- (piperidine-1-carbonyl) -1,2,3,4-tetrahydro-[1,4]diazepino[6.7.1-hi]indol-7-yl) -4- (imidazo[1.2-a]pyridine-3-yl) -1H-pyrrole-2,5-dione

Field of Research

Cell Biology, Stem Cell & Developmental Biology

Purity

>98%

Form

Powder

Solubility

Soluble in DMSO (up to at least 20 mg/ml)

Smiles

Fc1cc2CN (CCn3cc (C4=C (C (=O) NC4=O) c4cnc5ccccn45) c (c1) c23) C (=O) N1CCCCC1

Molecular Formula

C28H25FN6O3

Molecular Weight

512.5

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

3-[6-Fluoro-10- (piperidine-1-carbonyl) -1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8 (13) -tetraene-3-yl]-4-imidazo[1,2-a]pyridine-3-ylpyrrole-2,5-dione