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Ilaprazole sodium

Ilaprazole sodium (IY-81149 sodium) is an irreversible proton pump inhibitor prodrug. It is activated in acidic parietal cell compartments to form a sulfenamide that covalently inhibits H+/K+ ATPase, suppressing gastric acid secretion. This compound is utilized in research on gastric ulcer models, acid-related disorders, and the pharmacodynamics of PPI mechanisms in both in vitro and in vivo experimental settings.

Product Specifications

CAS Number

172152-50-0

Product Name Alternative

Cancer, acid, IY81149, IY-81149, IY-81149 sodium, IY 81149, Ilaprazole, Ilaprazole sodium, inhibit, oral, Inhibitor, gastric, pump, Proton pump, Protonpump, Proton Pump, TOPK, ulcers

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Purity

97.71% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.15 mM) ; DMSO:71 mg/mL (182.79 mM) ; H2O:50 mg/mL (128.73 mM)

Smiles

O=S (CC1=NC=CC (OC) =C1C) C2=NC3=C ([N-]2) C=C (N4C=CC=C4) C=C3.[Na+]

Molecular Formula

C19H17N4NaO2S

Molecular Weight

388.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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