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ABT-751

ABT-751 (E7010) is a small molecule antimitotic agent that has been studied in preclinical and clinical research for non-small cell lung cancer (NSCLC) . Its mechanism involves inhibiting tubulin polymerization, and it has demonstrated antitumor activity in both in vitro cell assays and in vivo xenograft models.

Product Specifications

CAS Number

141430-65-1

Product Name Alternative

E 7010, ABT751, ABT-751, ABT 751, Autophagy, inhibit, microtubule, Microtubule Associated, Microtubule/Tubulin, MicrotubuleAssociated, Inhibitor, E7010, E-7010

Field of Research

Cell Biology, Signal Transduction

Purity

98.84% (May vary between batches)

Solubility

DMSO:37.1 mg/mL (99.89 mM) ; Ethanol:9.3 mg/mL (25.04 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.38 mM)

Smiles

COc1ccc (cc1) S (=O) (=O) Nc1cccnc1Nc1ccc (O) cc1

Molecular Formula

C18H17N3O4S

Molecular Weight

371.41

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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