ABT-751
ABT-751 (E7010) is a small molecule antimitotic agent that has been studied in preclinical and clinical research for non-small cell lung cancer (NSCLC) . Its mechanism involves inhibiting tubulin polymerization, and it has demonstrated antitumor activity in both in vitro cell assays and in vivo xenograft models.
Product Specifications
CAS Number
141430-65-1
Product Name Alternative
E 7010, ABT751, ABT-751, ABT 751, Autophagy, inhibit, microtubule, Microtubule Associated, Microtubule/Tubulin, MicrotubuleAssociated, Inhibitor, E7010, E-7010
Field of Research
Cell Biology, Signal Transduction
Purity
98.84% (May vary between batches)
Solubility
DMSO:37.1 mg/mL (99.89 mM) ; Ethanol:9.3 mg/mL (25.04 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.38 mM)
Smiles
COc1ccc (cc1) S (=O) (=O) Nc1cccnc1Nc1ccc (O) cc1
Molecular Formula
C18H17N3O4S
Molecular Weight
371.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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