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PD153035 hydrochloride

PD153035 hydrochloride is a potent and highly selective EGFR inhibitor with a Ki of 5.2 pM, demonstrating minimal activity against FGFR, PDGFR, and other kinases. It is widely used in cancer research to study EGFR-driven signaling pathways in both cellular and animal models of tumorigenesis.

Product Specifications

CAS Number

183322-45-4

Product Name Alternative

SU 5271, SU5271, SU-5271 Hcl, SU-5271, ZM252868, ZM-252868, ZM 252868 HCl, Tyrphostin AG 1517, Tyrphostin AG1517, Tyrphostin AG-1517, EGFR, PD 153035 Hydrochloride, PD 153035, PD-153035, PD153035 HCl, PD153035, AG 1517 Hcl, AG 1517, AG-1517, AG1517

Field of Research

Cardiovascular Research, Signal Transduction

Purity

≥95% (May vary between batches)

Solubility

DMSO:4 mg/mL (10.08 mM)

Smiles

Cl.COc1cc2ncnc (Nc3cccc (Br) c3) c2cc1OC

Molecular Formula

C16H15BrClN3O2

Molecular Weight

396.67

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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