PD153035 hydrochloride
PD153035 hydrochloride is a potent and highly selective EGFR inhibitor with a Ki of 5.2 pM, demonstrating minimal activity against FGFR, PDGFR, and other kinases. It is widely used in cancer research to study EGFR-driven signaling pathways in both cellular and animal models of tumorigenesis.
Product Specifications
CAS Number
183322-45-4
Product Name Alternative
SU 5271, SU5271, SU-5271 Hcl, SU-5271, ZM252868, ZM-252868, ZM 252868 HCl, Tyrphostin AG 1517, Tyrphostin AG1517, Tyrphostin AG-1517, EGFR, PD 153035 Hydrochloride, PD 153035, PD-153035, PD153035 HCl, PD153035, AG 1517 Hcl, AG 1517, AG-1517, AG1517
Field of Research
Cardiovascular Research, Signal Transduction
Purity
≥95% (May vary between batches)
Solubility
DMSO:4 mg/mL (10.08 mM)
Smiles
Cl.COc1cc2ncnc (Nc3cccc (Br) c3) c2cc1OC
Molecular Formula
C16H15BrClN3O2
Molecular Weight
396.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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