RGFP966

RGFP966 is a potent and selective HDAC3 inhibitor with an IC50 of 0.08 μM. It is widely used in research to investigate epigenetic mechanisms in neuroscience, oncology, and metabolic studies, with applications in both cellular and animal models.

Product Specifications

CAS Number

1357389-11-7

Product Name Alternative

RGFP 966, RGFP966, RGFP-966, Inhibitor, HDAC3, HDAC, Histone deacetylases, inhibit

Field of Research

Epigenetics & Chromatin, Neuroscience

Purity

>98%

Bioactivity

Selective HDAC3 inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 20 mg/ml)

Smiles

Nc1cc (F) ccc1NC (=O) \C=C\c1cnn (C\C=C\c2ccccc2) c1

Molecular Formula

C21H19FN4O

Molecular Weight

362.40

References & Citations

Rudy Matheson 1 & Kohei Chida 2 & Hui Lu 1,3 & Victoria Clendaniel 1 & Marc Fisher 4 & Ajith Thomas 5 & Eng H. Lo 6 & Magdy Selim 4 & Amjad Shehadah 4 Neuroprotective Effects of Selective Inhibition of Histone Deacetylase 3 in Experimental Stroke Ponatinib inhibitor, (2024)

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

(2E) -N- (2-Amino-4-fluorophenyl) -3-[ (2E) -1- (3-phenyl-2-propen-1-yl) -1H-pyrazol-4-yl]-2-propenamide

Available Sizes

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