BMH-21
BMH-21 is a small molecule that selectively intercalates into ribosomal DNA, thereby inhibiting RNA polymerase I transcription. It is a valuable research tool for studying nucleolar stress and ribosome biogenesis in both cellular and animal models, without inducing DNA damage signaling via H2AX phosphorylation.
Product Specifications
CAS Number
896705-16-1
Product Name Alternative
Damage, DNASynthesis, DNA/RNA Synthesis, DNA Synthesis, DNA, BMH21, BMH-21, BMH 21, inhibit, nucleolus, intercalation, Inhibitor, transcription, polymerase, RNASynthesis, RNA, RNA polymerase I, RNA Synthesis, response
Field of Research
Cell Biology
Purity
>98%
Bioactivity
RNA polymerase I inhibitor
Form
Powder
Solubility
Soluble in DMSO (13 mg/ml with warming)
Smiles
CN (C) CCNC (=O) c1cccn2c1nc1cc3ccccc3cc1c2=O
Molecular Formula
C21H20N4O2
Molecular Weight
360.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N-[2- (dimethylamino) ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide
Available Sizes
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