AT7519 Hydrochloride
AT7519 HCl is a potent, cell-permeable inhibitor targeting multiple cyclin-dependent kinases (CDKs), including CDK1, CDK2, CDK4, CDK6, and CDK9. It is widely used in biochemical and cellular research to study cell cycle progression and transcriptional regulation, demonstrating antitumor activity in both in vitro and in vivo cancer models.
Product Specifications
CAS Number
902135-91-5
Product Name Alternative
Cyclin dependent kinase, CDK4/CyclinD1, CDK5/p35, CDK9/CyclinT, CDK, CDK2/CyclinA, AT 7519, AT 7519 Hydrochloride, AT 7519 hydrochloride salt, AT7519, AT-7519, AT7519 HCl, AT7519 Hydrochloride, AT-7519 Hydrochloride, Apoptosis, GSK3, GSK-3β, inhibit, Inhibitor
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.66% (May vary between batches)
Solubility
DMSO:40 mg/mL (95.53 mM) ; Ethanol:28 mg/mL (66.87 mM) ; H2O:1 mg/mL (2.39 mM)
Smiles
Cl.Clc1cccc (Cl) c1C (=O) Nc1c[nH]nc1C (=O) NC1CCNCC1
Molecular Formula
C16H18Cl3N5O2
Molecular Weight
418.71
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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