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AT7519 Hydrochloride

AT7519 HCl is a potent, cell-permeable inhibitor targeting multiple cyclin-dependent kinases (CDKs), including CDK1, CDK2, CDK4, CDK6, and CDK9. It is widely used in biochemical and cellular research to study cell cycle progression and transcriptional regulation, demonstrating antitumor activity in both in vitro and in vivo cancer models.

Product Specifications

CAS Number

902135-91-5

Product Name Alternative

Cyclin dependent kinase, CDK4/CyclinD1, CDK5/p35, CDK9/CyclinT, CDK, CDK2/CyclinA, AT 7519, AT 7519 Hydrochloride, AT 7519 hydrochloride salt, AT7519, AT-7519, AT7519 HCl, AT7519 Hydrochloride, AT-7519 Hydrochloride, Apoptosis, GSK3, GSK-3β, inhibit, Inhibitor

Field of Research

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Purity

99.66% (May vary between batches)

Solubility

DMSO:40 mg/mL (95.53 mM) ; Ethanol:28 mg/mL (66.87 mM) ; H2O:1 mg/mL (2.39 mM)

Smiles

Cl.Clc1cccc (Cl) c1C (=O) Nc1c[nH]nc1C (=O) NC1CCNCC1

Molecular Formula

C16H18Cl3N5O2

Molecular Weight

418.71

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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