Canagliflozin
Canagliflozin is a potent and selective SGLT2 inhibitor with IC50 values of 2, 3.7, and 4.4 nM against mouse, rat, and human SGLT2, respectively. It is widely used in research for type 2 diabetes, enabling in vitro transport assays and in vivo studies of glycemic control and renal function.
Product Specifications
CAS Number
842133-18-0
Product Name Alternative
JNJ-24831754
Field of Research
Cell Biology
Purity
>98%
Bioactivity
SGLT2 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 40 mg/ml)
Smiles
O[C@H]1[C@@H] (O[C@H] (CO) [C@@H] (O) [C@@H]1O) C2=CC (CC=3SC (=CC3) C4=CC=C (F) C=C4) =C (C) C=C2
Molecular Formula
C24H25FO5S
Molecular Weight
444.5
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(1S) -1,5-anhydro-1-C-[3-[[5- (4-fluorophenyl) -2-thienyl]methyl]-4-methylphenyl]-D-glucitol
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