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E3 ligase Ligand 8

E3 ligase Ligand 8 serves as a recruiter for ubiquitin ligase in the construction of PROTAC molecules. These bifunctional degraders are widely utilized in both in vitro and in vivo cancer research to induce the targeted ubiquitination and subsequent proteasomal degradation of oncogenic proteins.

Product Specifications

CAS Number

1225383-33-4

Product Name Alternative

Inhibitor, inhibit, LigandforE3Ligase, Ligand for E3 Ligase, Ligands for E3 Ligase, E3 ligase-recruiting Moiety, E3 ligase Ligand 8, E-3 ligase Ligand 8

Field of Research

Molecular Biology, Pharmacology & Drug Discovery

Purity

98.12% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.22 mM) ; DMSO:90 mg/mL (169.62 mM)

Smiles

CC (C) C[C@H] (NC (=O) [C@@H] (O) [C@@H] (Cc1ccccc1) NC (=O) OCC1c2ccccc2-c2ccccc12) C (O) =O

Molecular Formula

C31H34N2O6

Molecular Weight

530.61

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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