E3 ligase Ligand 8
E3 ligase Ligand 8 serves as a recruiter for ubiquitin ligase in the construction of PROTAC molecules. These bifunctional degraders are widely utilized in both in vitro and in vivo cancer research to induce the targeted ubiquitination and subsequent proteasomal degradation of oncogenic proteins.
Product Specifications
CAS Number
1225383-33-4
Product Name Alternative
Inhibitor, inhibit, LigandforE3Ligase, Ligand for E3 Ligase, Ligands for E3 Ligase, E3 ligase-recruiting Moiety, E3 ligase Ligand 8, E-3 ligase Ligand 8
Field of Research
Molecular Biology, Pharmacology & Drug Discovery
Purity
98.12% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.22 mM) ; DMSO:90 mg/mL (169.62 mM)
Smiles
CC (C) C[C@H] (NC (=O) [C@@H] (O) [C@@H] (Cc1ccccc1) NC (=O) OCC1c2ccccc2-c2ccccc12) C (O) =O
Molecular Formula
C31H34N2O6
Molecular Weight
530.61
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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