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Itraconazole

Itraconazole (R51211) is an orally active triazole antifungal agent that also acts as a Hedgehog pathway antagonist, an OSBP inhibitor, and a cytochrome P450 enzyme inhibitor. It is widely used in research for studying antifungal mechanisms, cancer signaling pathways, and lipid transport in both in vitro and in vivo models.

Product Specifications

CAS Number

84625-61-6

Product Name Alternative

Oriconazole; R51211

Field of Research

Cardiovascular Research, Cell Biology

Purity

>98%

Bioactivity

Autophagy inducer; Inhibits glioblastoma growth

Form

Powder

Solubility

Soluble in DMSO (up to 1.5 mg/ml with warming)

Smiles

C ([C@]1 (O[C@@H] (COC2=CC=C (C=C2) N3CCN (CC3) C4=CC=C (C=C4) N5C (=O) N (C (CC) C) N=C5) CO1) C6=C (Cl) C=C (Cl) C=C6) N7C=NC=N7

Molecular Formula

C35H38Cl2N8O4

Molecular Weight

705.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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