AES-135
AES-135 is a potent small molecule inhibitor of HDAC3, HDAC6, and HDAC11 with IC50 values of 654, 190, and 636 nM, respectively. It exhibits anti-tumor activity and is a useful research tool for studying epigenetics and oncology in both cellular and animal models of cancer.
Product Specifications
CAS Number
2361659-61-0
Product Name Alternative
AES135, AES-135, AES 135, anti-tumor, inhibit, pancreatic, Inhibitor, HDAC, HDAC11, HDAC3, HDAC6, Histone deacetylases
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
97.72% (May vary between batches)
Solubility
DMSO:100 mg/mL (144.16 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (4.76 mM)
Smiles
CC (C) (C) c1ccc (CN (C (=O) CN (Cc2c (F) c (F) c (F) c (F) c2F) S (=O) (=O) c2ccc (F) cc2) c2ccc (cc2) C (=O) NO) cc1
Molecular Formula
C33H29F6N3O5S
Molecular Weight
693.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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