AES-135
AES-135 is a potent small molecule inhibitor of HDAC3, HDAC6, and HDAC11 with IC50 values of 654, 190, and 636 nM, respectively. It exhibits anti-tumor activity and is a useful research tool for studying epigenetics and oncology in both cellular and animal models of cancer.
Product Specifications
CAS Number
2361659-61-0
Product Name Alternative
AES135, AES-135, AES 135, anti-tumor, inhibit, pancreatic, Inhibitor, HDAC, HDAC11, HDAC3, HDAC6, Histone deacetylases
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
97.72% (May vary between batches)
Solubility
DMSO:100 mg/mL (144.16 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (4.76 mM)
Smiles
CC (C) (C) c1ccc (CN (C (=O) CN (Cc2c (F) c (F) c (F) c (F) c2F) S (=O) (=O) c2ccc (F) cc2) c2ccc (cc2) C (=O) NO) cc1
Molecular Formula
C33H29F6N3O5S
Molecular Weight
693.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Aurkb, NT (Aurkb, Aik2, Aim1, Airk2, Ark2, Stk1, Stk12, Stk5, Aurora kinase B, Aurora 1, Aurora-and IPL1-like midbody-associated protein 1, Aurora/IPL1-related kinase 2, STK-1, Serine/threonine-protein kinase 12, Serine/threonine-protein kinase 5, Serine/
Aurkb, NT (Aurkb, Aik2, Aim1, Airk2, Ark2, Stk1, Stk12, Stk5, Aurora kinase B, Aurora 1, Aurora-and IPL1-like midbody-associated protein 1, Aurora/IPL1-related kinase 2, STK-1, Serine/threonine-protein kinase 12, Serine/threonine-protein kinase 5, Serine/