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Anamorelin

Anamorelin (ONO-7643) is a potent and selective ghrelin receptor agonist, demonstrating an EC50 of 0.74 nM in FLIPR-based assays. It is utilized in research on cancer cachexia, appetite stimulation, and muscle wasting, with applications in both in vitro mechanistic studies and in vivo animal models.

Product Specifications

CAS Number

249921-19-5

Product Name Alternative

Anamorelin, inhibit, ONO 7643, ONO7643, ONO-7643, Inhibitor, Growth hormone secretagogue receptor, GHSR, GHS-R, ghrelin receptor, RC1291, RC-1291, RC 1291

Field of Research

Pharmacology & Drug Discovery

Purity

99.35% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.66 mM) ; DMSO:250 mg/mL (457.29 mM)

Smiles

CN (C) N (C) C (=O) [C@@]1 (Cc2ccccc2) CCCN (C1) C (=O) [C@@H] (Cc1c[nH]c2ccccc12) NC (=O) C (C) (C) N

Molecular Formula

C31H42N6O3

Molecular Weight

546.7

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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