Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

APTO-253

APTO-253 is a small molecule that stabilizes G-quadruplex DNA, leading to c-Myc downregulation and KLF4 tumor suppressor induction. This mechanism results in cell cycle arrest and apoptosis in acute myeloid leukemia (AML) cells, as demonstrated in in vitro studies. Its activity makes it a candidate for oncology research, particularly in hematological malignancies.

Product Specifications

CAS Number

916151-99-0

Product Name Alternative

CMyc, c-Myc, Apoptosis, APTO253, APTO-253, APTO 253, LT253, LT-253, LT 253, inhibit, Myc, KLF, Krüppel-like factor, LOR 253, LOR253, LOR-253, Inhibitor

Field of Research

Cell Biology, Signal Transduction

Purity

98.73% (May vary between batches)

Solubility

DMSO:35.71 mg/mL (97.2 mM)

Smiles

Cc1[nH]c2ccc (F) cc2c1-c1nc2c ([nH]1) c1cccnc1c1ncccc21

Molecular Formula

C22H14FN5

Molecular Weight

367.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Rat Rasgrp2 ELISA Kit
ELI-19411r 96 Tests

Rat Rasgrp2 ELISA Kit

Sign In for Pricing
View Details
Human GH1/Somatotropin ELISA Kit
EK00127E 96 Tests

Human GH1/Somatotropin ELISA Kit

Sign In for Pricing
View Details
mmu-miR-6345 Primers
MPM01472 150 µL - 10 µM

mmu-miR-6345 Primers

Sign In for Pricing
View Details
PARK7 rabbit pAb
ES3150-01 50 µL

PARK7 rabbit pAb

Sign In for Pricing
View Details
PARK7 rabbit pAb
ES3150-02 100 µL

PARK7 rabbit pAb

Sign In for Pricing
View Details
Lentiviral human TOE1 shRNA (UAS) - Lentiviral human TOE1 shRNA (UAS, RFP) (25)
GTR15296342 1 Vial

Lentiviral human TOE1 shRNA (UAS) - Lentiviral human TOE1 shRNA (UAS, RFP) (25)

Sign In for Pricing
View Details