AR antagonist 1
AR antagonist 1 is a potent androgen receptor (AR) antagonist utilized in the development of PROTAC ARD-266. This compound incorporates a VHL E3 ligase ligand, enabling targeted protein degradation. It serves as a key chemical probe for studying AR function in prostate cancer research, both in vitro and in vivo.
Product Specifications
CAS Number
1818885-54-9
Product Name Alternative
E3 ligase-recruiting Moiety, AR antagonist 1, AR antagonist1, AR antagonist-1, Androgen Receptor, androgen receptor, AndrogenReceptor, cancer, Inhibitor, LNCaP, Ligands for E3 Ligase, LigandforE3Ligase, Ligand for E3 Ligase, LigandsforTargetProteinforPROTAC, Ligands for Target Protein for PROTAC, Linker, inhibit, Target Protein-binding Moiety, PROTAC, tumor, VCaP
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
98.96% (May vary between batches)
Solubility
DMSO:60 mg/mL (215.22 mM)
Smiles
CC1 (C) [C@H] (N) C (C) (C) [C@H]1Oc1ccc (C#N) c (Cl) c1
Molecular Formula
C15H19ClN2O
Molecular Weight
278.78
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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