AWZ1066S
AWZ1066S is a potent and selective anti-Wolbachia agent, demonstrating an EC50 of 2.5 nM in cellular assays. It is a promising candidate for abbreviated filariasis treatment regimens, with research applications in both in vitro mechanistic studies and in vivo animal models of filarial infection.
Product Specifications
CAS Number
2239272-16-1
Product Name Alternative
CYP3A4, CYP2C9, AWZ1066S, AWZ-1066S, anti-Wolbachia, Inhibitor, inhibit, lymphatic filariasis (elephantiasis), Onchocerciasis (river blindness), oral, Parasite, tropical diseases
Field of Research
Infectious Disease & Virology
Purity
98.32% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.89 mM) ; DMSO:120 mg/mL (296.74 mM)
Smiles
C[C@H]1COCCN1c1nc (NCc2cccnc2C (F) (F) F) c2cccnc2n1
Molecular Formula
C19H19F3N6O
Molecular Weight
404.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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