AZ084
AZ084 is a potent and selective allosteric CCR8 antagonist with oral bioavailability, exhibiting a Ki of 0.9 nM. It is a valuable research tool for investigating CCR8 biology in asthma and other inflammatory diseases, with applications in both in vitro binding assays and in vivo preclinical models.
Product Specifications
CAS Number
929300-19-6
Product Name Alternative
Inhibitor, inhibit, PMN, asthma, AZ084, AZ-084, AZ 084, CCR, CC chemokine receptor, CCR8, tumor metastasis, Tregs differentiation, T cells
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
97.12% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.51 mM) ; DMSO:240 mg/mL (552.27 mM)
Smiles
CC1 (C) Cc2c (O1) cccc2CN1CCC2 (CC1) CCN (CC2) C (=O) c1ccc (N) cn1
Molecular Formula
C26H34N4O2
Molecular Weight
434.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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