Golidocitinib
Golidocitinib (AZD4205) is a potent and selective JAK1 inhibitor with an IC50 of 73 nM, demonstrating minimal activity against JAK2 and JAK3. It is a valuable research tool for investigating JAK/STAT signaling in immunological and inflammatory diseases, with utility in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2091134-68-6
Product Name Alternative
AZD 4205, AZD4205, AZD-4205, Golidocitinib, Inhibitor, inhibit, Janus kinase, JAK, JAK1
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.87% (May vary between batches)
Solubility
DMSO:250 mg/mL (510.65 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.21 mM)
Smiles
COc1nn (C) cc1Nc1nccc (n1) -c1c[nH]c2c (NC (=O) [C@@H] (C) N3CCN (C) CC3) cccc12
Molecular Formula
C25H31N9O2
Molecular Weight
489.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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