Azosemide
Azosemide is a potent and selective inhibitor of the human NKCC1 transporter, demonstrating low micromolar IC50 values. This loop diuretic is a valuable research tool for studying ion transport mechanisms in physiological and disease contexts, including hypertension and edema, in both cellular and animal models.
Product Specifications
CAS Number
27589-33-9
Product Name Alternative
Azosemide, diuretic, inhibit, Inhibitor, loop, NaKCl cotransporter, Na-K-Cl cotransporter, NaKClcotransporter, NKCC, NKCC1, NKCC1B, hNKCC1A, sulfonamide
Field of Research
Pharmacology & Drug Discovery
Purity
98.93% (May vary between batches)
Solubility
DMSO:249 mg/mL (671.45 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (13.48 mM)
Smiles
NS (=O) (=O) c1cc (-c2nnn[nH]2) c (NCc2cccs2) cc1Cl
Molecular Formula
C12H11ClN6O2S2
Molecular Weight
370.84
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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