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Mexiletine hydrochloride

Mexiletine hydrochloride is a Class IB antiarrhythmic agent that functions as a voltage-gated sodium channel blocker. It is widely used in cardiovascular research to study arrhythmia mechanisms, employing both in vitro electrophysiology and in vivo animal models to investigate its modulation of cardiac action potentials and Purkinje fiber automaticity.

Product Specifications

CAS Number

5370-01-4

Product Name Alternative

Na+ channels, Na channels, Mexiletine, Mexiletine HCl, Mexiletine hydrochloride, Mexiletine Hydrochloride, KOE 1173, KOE1173, KOE-1173, KOE-1173 (hydrochloride), KO 1173, KO1173, KO-1173, inhibit, myocardial, ischemia, Inhibitor, Class IB, AhR, antiarrhythmic, Sodium Channel, SodiumChannel, Voltage-gated sodium channel

Field of Research

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery

Purity

98.44% (May vary between batches)

Solubility

H2O:21.6 mg/mL (100.13 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.27 mM) ; DMSO:50 mg/mL (231.78 mM)

Smiles

Cl.CC (N) COc1c (C) cccc1C

Molecular Formula

C11H18ClNO

Molecular Weight

215.72

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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