Mexiletine hydrochloride
Mexiletine hydrochloride is a Class IB antiarrhythmic agent that functions as a voltage-gated sodium channel blocker. It is widely used in cardiovascular research to study arrhythmia mechanisms, employing both in vitro electrophysiology and in vivo animal models to investigate its modulation of cardiac action potentials and Purkinje fiber automaticity.
Product Specifications
CAS Number
5370-01-4
Product Name Alternative
Na+ channels, Na channels, Mexiletine, Mexiletine HCl, Mexiletine hydrochloride, Mexiletine Hydrochloride, KOE 1173, KOE1173, KOE-1173, KOE-1173 (hydrochloride), KO 1173, KO1173, KO-1173, inhibit, myocardial, ischemia, Inhibitor, Class IB, AhR, antiarrhythmic, Sodium Channel, SodiumChannel, Voltage-gated sodium channel
Field of Research
Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery
Purity
98.44% (May vary between batches)
Solubility
H2O:21.6 mg/mL (100.13 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.27 mM) ; DMSO:50 mg/mL (231.78 mM)
Smiles
Cl.CC (N) COc1c (C) cccc1C
Molecular Formula
C11H18ClNO
Molecular Weight
215.72
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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