BAY-1816032
BAY-1816032 is a potent, orally active BUB1 kinase inhibitor with an IC50 of 0.7 nM. It effectively blocks BUB1-mediated histone H2A phosphorylation in cellular assays and is a valuable chemical probe for investigating mitosis, chromosomal instability, and cancer biology in both in vitro and in vivo research models.
Product Specifications
CAS Number
1891087-61-8
Product Name Alternative
BUB1, BUB1 kinase, BAY 1816032, BAY1816032, BAY-1816032, inhibit, Inhibitor
Field of Research
Cell Biology, Metabolism Research
Purity
98.02% (May vary between batches)
Solubility
H2O:< 0.1 mg/mL (insoluble) ; DMSO:15 mg/mL (28.06 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.74 mM)
Smiles
COc1cnccc1Nc1nc (ncc1OC) -c1nn (Cc2c (F) cc (OCCO) cc2F) c2ccccc12
Molecular Formula
C27H24F2N6O4
Molecular Weight
534.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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