Bisindolylmaleimide VIII acetate
Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent, selective inhibitor of protein kinase C (PKC), with IC50 values ranging from 53 to 213 nM across multiple PKC isoforms. It is widely used in biochemical research to investigate PKC-mediated signaling pathways in cellular and animal models of cancer, inflammation, and neurological disorders.
Product Specifications
CAS Number
138516-31-1
Product Name Alternative
Cell-mediated, diseases, Bisindolylmaleimide VIII, Bisindolylmaleimide VIII acetate, Bisindolylmaleimide VIII Acetate, Bis VIII, Bis VIII acetate, Bis VIII Acetate, autoimmune, Apoptosis, Inhibitor, kinase, inhibit, Fas, Ro 31-7549, Ro 31-7549 acetate, Ro 31-7549 Acetate, Protein kinase C, protein, PKC, PKCα, PKC-α, PKCβ2, PKCβ1, PKC-βI, PKC-βII, PKCε, PKC-ε, PKCγ, PKC-γ, Rat Brain PKC
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
99.00% (May vary between batches)
Solubility
DMSO:55 mg/mL (119.95 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.36 mM)
Smiles
CC (O) =O.Cn1cc (C2=C (C (=O) NC2=O) c2cn (CCCN) c3ccccc23) c2ccccc12
Molecular Formula
C26H26N4O4
Molecular Weight
458.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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