Ifosfamide
Ifosfamide is a nitrogen mustard prodrug analog of cyclophosphamide, activated by liver enzymes to alkylate DNA and form crosslinks, inhibiting strand separation and replication. It is widely used in cancer research, including in vitro cytotoxicity assays and in vivo xenograft studies for various solid tumors and lymphomas.
Product Specifications
CAS Number
3778-73-2
Product Name Alternative
Crosslinker, DNA/RNA Synthesis, DNA Synthesis, DNASynthesis, DNAAlkylator, DNA Alkylator, DNA Alkylator/Crosslinker, Inhibitor, Ifosfamide, NSC109724, NSC-109724, NSC 109724, inhibit, Isophosphamide, RNASynthesis, RNA Synthesis
Field of Research
Cell Biology, Molecular Biology, Pharmacology & Drug Discovery
Purity
≥95% (May vary between batches)
Solubility
Ethanol:49 mg/mL (187.67 mM) ; DMSO:250 mg/mL (957.52 mM) ; H2O:48 mg/mL (183.84 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.66 mM)
Smiles
ClCCNP1 (=O) OCCCN1CCCl
Molecular Formula
C7H15Cl2N2O2P
Molecular Weight
261.09
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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