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Fostemsavir Tris

Fostemsavir Tris (BMS-663068 Tris) is an oral prodrug of the active attachment inhibitor BMS-626529. It blocks HIV-1 infection by binding to viral gp120, preventing its attachment to host CD4+ T-cells. This mechanism has been validated in both in vitro antiviral assays and in vivo clinical research for antiretroviral therapy.

Product Specifications

CAS Number

864953-39-9

Product Name Alternative

BMS663068, BMS-663068, BMS-663068 Tris, BMS 663068, inhibit, Inhibitor, HIV, HIV Protease, HIV-1, HIVProtease, Fostemsavir, Fostemsavir Tris, Human immunodeficiency virus

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Purity

99.45% (May vary between batches)

Solubility

H2O:100 mg/mL (141.92 mM) ; DMSO:125 mg/mL (177.4 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (5.68 mM)

Smiles

O=C (N1CCN (C (C2=CC=CC=C2) =O) CC1) C (C3=CN (COP (O) (O) =O) C4=C3C (OC) =CN=C4N5N=C (C) N=C5) =O.OCC (CO) (N) CO

Molecular Formula

C29H37N8O11P

Molecular Weight

704.62

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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