BMT-145027
BMT-145027 is a selective positive allosteric modulator (PAM) of the mGluR5 receptor, exhibiting an EC50 of 47 nM with no intrinsic agonist activity. This compound is a valuable research tool for investigating mGluR5 function in neurological disorders, facilitating both in vitro binding studies and in vivo behavioral models.
Product Specifications
CAS Number
2018282-44-3
Product Name Alternative
Inhibit, Inhibitor, Metabotropic glutamate receptors, mGluR, mGluR5, BMT145027, BMT-145027, BMT 145027
Field of Research
Neuroscience
Purity
99.50% (May vary between batches)
Solubility
DMSO:2 mg/mL (4.56 mM)
Smiles
FC (F) (F) c1cc (ccc1Cl) -c1n[nH]c2nc (-c3ccccc3) c (C#N) c (C3CC3) c12
Molecular Formula
C23H14ClF3N4
Molecular Weight
438.83
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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