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BMT-145027

BMT-145027 is a selective positive allosteric modulator (PAM) of the mGluR5 receptor, exhibiting an EC50 of 47 nM with no intrinsic agonist activity. This compound is a valuable research tool for investigating mGluR5 function in neurological disorders, facilitating both in vitro binding studies and in vivo behavioral models.

Product Specifications

CAS Number

2018282-44-3

Product Name Alternative

Inhibit, Inhibitor, Metabotropic glutamate receptors, mGluR, mGluR5, BMT145027, BMT-145027, BMT 145027

Field of Research

Neuroscience

Purity

99.50% (May vary between batches)

Solubility

DMSO:2 mg/mL (4.56 mM)

Smiles

FC (F) (F) c1cc (ccc1Cl) -c1n[nH]c2nc (-c3ccccc3) c (C#N) c (C3CC3) c12

Molecular Formula

C23H14ClF3N4

Molecular Weight

438.83

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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