Bozitinib
Bozitinib (PLB-1001) is a brain-penetrant, highly selective c-MET kinase inhibitor that targets the ATP-binding site. It is utilized in preclinical oncology research, showing activity in both in vitro assays and in vivo models of cancers with c-MET dysregulation.
Product Specifications
CAS Number
1440964-89-5
Product Name Alternative
Inhibitor, HGFR, inhibit, PLB 1001, PLB1001, PLB-1001, Bozitinib, c-Met/HGFR, cMet/HGFR, c-Met, cMet, CBT 101, CBT101, CBT-101, Vebreltinib
Field of Research
Signal Transduction
Purity
99.16% (May vary between batches)
Solubility
DMSO:30 mg/mL (70.69 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.71 mM)
Smiles
Cn1cc2cc (c (F) cc2n1) C (F) (F) c1nnc2ccc (nn12) -c1cnn (c1) C1CC1
Molecular Formula
C20H15F3N8
Molecular Weight
424.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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