BPH-1358
BPH-1358 (NSC-50460) is a dual inhibitor of human FPPS and bacterial UPPS with IC50 values of 1.8 μM and 110 nM, respectively. It exhibits in vitro antibacterial activity against S. aureus (MIC ~250 ng/mL) and serves as a research tool for studying isoprenoid biosynthesis and antimicrobial strategies.
Product Specifications
CAS Number
5352-53-4
Product Name Alternative
Bacterial, BPH 1358, BPH1358, BPH-1358, inhibit, Inhibitor, NSC 50460, NSC50460, NSC-50460, FPPS, human bisphosphonate farnesyl diphosphate synthase
Field of Research
Infectious Disease & Virology
Purity
99.63% (May vary between batches)
Solubility
DMSO:Slightly soluble
Smiles
O=C (C1=CC=C (C2=CC=C (C (NC3=CC=CC (C4=NCCN4) =C3) =O) C=C2) C=C1) NC5=CC=CC (C6=NCCN6) =C5.[H]Cl.[H]Cl
Molecular Formula
C32H30Cl2N6O2
Molecular Weight
601.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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