Zatolmilast
Zatolmilast (BPN14770) is a potent allosteric inhibitor of PDE4D, exhibiting IC50 values of 7.8 nM and 7.4 nM against the PDE4D7 and PDE4D3 isoforms, respectively. This compound is a valuable research tool for investigating PDE4D's role in neurobiology and cognitive function, with applications in both in vitro and in vivo models.
Product Specifications
CAS Number
1606974-33-7
Product Name Alternative
BPN 14770, BPN14770, BPN-14770, inhibit, Inhibitor, Zatolmilast, PDE4D3, PDE4D7, Phosphodiesterase (PDE), phosphodiesterase
Field of Research
Metabolism Research
Purity
98.20% (May vary between batches)
Solubility
DMSO:260 mg/mL (640.71 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.32 mM)
Smiles
OC (=O) Cc1ccc (Cc2cc (nc (c2) C (F) (F) F) -c2cccc (Cl) c2) cc1
Molecular Formula
C21H15ClF3NO2
Molecular Weight
405.8
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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