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BRD0705

BRD0705 is a potent, orally bioavailable small molecule inhibitor with significant selectivity for GSK3α over GSK3β. It is a valuable research tool for investigating the distinct roles of GSK3 paralogs in cellular signaling, proliferation, and in vivo models of disease.

Product Specifications

CAS Number

2056261-41-5

Product Name Alternative

β-catenin, survival, GSK-3β (WT), GSK-3α, GSK3α, GSK-3, GSK3, Glycogen synthase kinase-3, Glycogen synthase kinase 3, leukemia, Inhibitor, oral, inhibit, kinase, myeloid, BRD 0705, BRD0705, BRD-0705, bioavailability, Acute

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Purity

99.01% (May vary between batches)

Solubility

DMSO:300 mg/mL (933.36 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (15.56 mM)

Smiles

CC[C@@]1 (C2=CNNC2=NC2=C1C (=O) CC (C) (C) C2) c1ccccc1

Molecular Formula

C20H23N3O

Molecular Weight

321.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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