C-021 dihydrochloride
C-021 dihydrochloride is a potent and selective CCR4 antagonist, effectively blocking chemotaxis in both human and mouse cells with IC50 values of 140 nM and 39 nM, respectively. This compound is a valuable research tool for studying CCR4-mediated immune responses in various in vitro and in vivo models of inflammation, allergy, and cancer.
Product Specifications
CAS Number
1784252-84-1
Product Name Alternative
CCR, CCL22, C021, C-021, C021 dihydrochloride, C021 Dihydrochloride, C-021 Dihydrochloride, C 021, C 021 dihydrochloride, C 021 Dihydrochloride, CC chemokine receptor, CCR4, chemotaxis, inhibit, Inhibitor, GTPγS
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
98.51% (May vary between batches)
Solubility
DMSO:5.41 mg/mL (10.01 mM) ; H2O:9.25 mg/mL (17.11 mM)
Smiles
Cl.Cl.COc1cc2nc (nc (NC3CCCCCC3) c2cc1OC) N1CCC (CC1) N1CCCCC1
Molecular Formula
C27H43Cl2N5O2
Molecular Weight
540.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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