C-Kit-IN-3
C-Kit-IN-3 is a potent and selective c-KIT kinase inhibitor, demonstrating IC50 values of 4 nM against wild-type and 8 nM against the T670I mutant. This small molecule is a valuable research tool for investigating c-KIT-driven pathologies, such as gastrointestinal stromal tumors (GIST), in both cellular and animal model studies.
Product Specifications
CAS Number
2363169-01-9
Product Name Alternative
C Kit IN 3, cKit, c-Kit, c-KIT w, cKitIN3, c-Kit-IN-3, c-KIT T670I
Field of Research
Signal Transduction
Purity
99.43% (May vary between batches)
Solubility
DMSO:100 mg/mL (193.46 mM)
Smiles
O (C=1C2=C (C=C (OC) C (OC) =C2) N=CC1) C3=CC=C (NC (CC4=CC (C (F) (F) F) =C (Cl) C=C4) =O) C=C3
Molecular Formula
C26H20ClF3N2O4
Molecular Weight
516.9
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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